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Symbol
Name
ID
Msh5
mutS homolog 5
MGI:1329021
Phenotype annotations related to reproductive system
Darker colors indicate more annotations
Human Phenotypes
Hypoplasia of the uterus
Amenorrhea
Oligomenorrhea
Female infertility
Disease(s) Associated with MSH5
primary ovarian insufficiency 13

Mouse Phenotypes
decreased oocyte number
absent oocytes
azoospermia
abnormal female meiosis
abnormal male meiosis
arrest of male meiosis
abnormal synaptonemal complex
increased male germ cell apoptosis
abnormal ovarian follicle morphology
absent ovarian follicles
small ovary
ovary atrophy
ovary cyst
ovary degeneration
decreased testis weight
small testis
increased granulosa cell tumor incidence
female infertility
male infertility
Availability Mouse Genotype
Msh5em1Jzc/Msh5em1Jzc
Msh5tm1Htr/Msh5tm1Htr
Msh5tm1Rak/Msh5tm1Rak

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory